A woman cut her hand which of these causes inflammation?
- Histamine
- Interlukin 1
- Interlukin 2
- Both A and B
Explanation
For a cut hand, both histamine and interleukin-1 (IL-1) cause inflammation.
Interleukin-2 (IL-2), while important for immune regulation, is not a primary or direct cause of the initial inflammatory response to an injury.
Histamine
- Released immediately by mast cells, which are a type of white blood cell located under the skin and near blood vessels.
- Acts quickly to increase blood flow to the injured area, causing the redness and swelling associated with inflammation.
Interleukin-1 (IL-1)
- A "master cytokine" for inflammation that is released by white blood cells like macrophages and monocytes.
- The IL-1α precursor is stored in skin cells (keratinocytes) and released rapidly upon injury.
Interleukin-2 (IL-2)
- A cytokine that promotes the growth and proliferation of T-cells and other lymphocytes
- It is part of the later adaptive immune response.
- IL-2 deficiency is linked to autoimmune diseases because it helps to maintain immune tolerance by promoting regulatory T-cells.
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